Dynamic organic chemistry

The aim of the course is to give students a better understanding of the reactivity of the main chemical functions, based on their chemical properties (acid/base, electrophile/nucleophile, hard/soft, oxidizing/reducing). Particular attention will be paid to reaction mechanisms and the reaction intermediates involved (radicals, carbocations and carbanions).
Targeted knowledge and skills:
- know the main organic chemistry functions, their physico-chemical properties and the main reactions associated with them
- correctly represent an organic molecule, taking into account its stereochemistry
- be able to determine the single or multiple reactivity of a molecule
- understand the reaction mechanisms involved and be able to describe them in accordance with writing conventions.
- predict the structure of a reaction product as a function of the reagents and conditions employed
- modify the functional properties of an organic molecule.

- Descriptive organic chemistry course on the basics of organic chemistry (BACOR) from S5
- Classes préparatoires courses
- Be able to identify the functions common in organic chemistry
- Know and use the rules of nomenclature (IUPAC and usual)
- Be able to represent a molecule using the different representations (Cram, Newman and Fisher)
- Be able to identify the electronic effects of a molecule (inductive and mesomeric)
- Distinguish between conformations and configurations
- Distinguish between relative and absolute stereochemistry
- Determine the stereochemistry of an asymmetric center

1 - Aliphatic hydrocarbons
1.1. Physico-chemical properties
1.2. Reactivity of alkanes and cycloalkanes (oxidation, cracking, radical halogenation)

2 - Ethylenic and acetylenic hydrocarbons
2.1. - General information and properties of alkenes and alkynes
2.2. - Reactivity associated with alkenes and alkynes (addition reactions (electrophilic, radical, concerted and 1,4 addition of soft nucleophiles such as malonates), dihalogenation, reduction and oxidation)

3 - Halogenides
3.1 - General information and properties of the carbon-halogen bond
3.2 - Halogenide reactivity (Nucleophilic substitutions (SN1 and SN2), elimination reactions (E1, E2 and E1cb), SN/E competition, carbocation rearrangement)

Thematic Molecular and Polymer Chemistry

Cours de chimie organique (Paul Arnaud) - Dunod
Traité de chimie organique (Peter Vollhardt and Neil Schore) - De boeck