School / Prep
ENSMAC
Internal code
PI6COREA
Description
The aim of the course is to provide training in descriptive organic chemistry. The main organic functions (unsaturated hydrocarbons, halogenated derivatives, alcohols and carbonyl derivatives) will be studied, along with the reactivity specific to each of them. In particular, this course will focus on the chemical transformation of functional groups via the breaking or creation of specific bonds. In some cases, an introduction to reaction mechanisms will be provided.
The course will be illustrated by specific examples and exercises to help you better understand the reactivity of compounds towards electrophilic (additions and substitutions), nucleophilic (additions, substitutions and eliminations) or radical species.
Teaching hours
- CIIntegrated courses29,33h
Mandatory prerequisites
S5 organic chemistry course
Syllabus
1 - Ethylenic and acetylenic hydrocarbons
1.1. - General information on alkenes and alkynes
1.2. - Reactivity of alkenes and alkynes / Regio- and Stereoselectivity
1.2.1 - Reactivities of alkenes (electrophilic, radical, nucleophilic additions, reduction and oxidation)
1.2.2.- Reactivity of alkynes (electrophilic additions, reduction)
2 - Halides
2.1 - General
2.2 - Reactivity of halides
2.2.1 - Nucleophilic substitutions (SN1 and SN2)
2.2.2 - Elimination reactions (E1 and E2)
3 - Aromatic compounds
3.1 - Aromaticity and aromatic compounds
3.2 - Reactivity of aromatic-benzene compounds
3.2.1 - Addition reactions (chlorination, hydrogenation)
3.2.2 - Aromatic electrophilic substitutions (nitration, halogenation, sulfonation, Friedel and Crafts)
3.2.3 - Influence of substituents on aromatic electrophilic substitution
4 - Alcohols
4.1 - General
4.2 - Reactivity of alcohols
4.2.1 - Acido-basicity
4.2.2 - Modification of the C-O bond (halide synthesis, elimination, esterification, oxidation)
4.2.3 - Reactivities (additions, electrophilic and nucleophilic substitutions)
5 -Carbonyl derivatives
5.1 - Overview
5.2 - Reactivity of aldehydes and ketones
6.2.1 - Nucleophilic additions
6.2.2 - Reduction of carbonyl derivatives
6.2.3 - Oxidation of aldehydes
6.2.4 - Reactivity linked to the acidity of H at carbonyl
Further information
Molecular and Polymer Chemistry
Bibliography
Cours de chimie organique, Paul Arnaud, Dunod
Chimie Organique Avancée, F.A. Carey and R.J. Sundberg, De Boeck Université, 1997
Assessment of knowledge
Initial assessment / Main session - Tests
Type of assessment | Type of test | Duration (in minutes) | Number of tests | Test coefficient | Eliminatory mark in the test | Remarks |
---|---|---|---|---|---|---|
Final inspection | Written | 60 | 1 |
Second chance / Catch-up session - Tests
Type of assessment | Type of test | Duration (in minutes) | Number of tests | Test coefficient | Eliminatory mark in the test | Remarks |
---|---|---|---|---|---|---|
Final test | Written | 60 | 1 |