Mammalian Cell Biology III: Genome

At the end of the "Genome" course, students will have acquired a global vision of the mechanisms regulating gene expression in mammals. This will enable them to use these notions to master the concepts of recombinant protein expression in mammalian cells. They will also have acquired knowledge of gene therapy and cell therapy approaches.

1A courses: Microbial Cell Biology and Genetic Engineering Methodology I and II

Presentation/understanding of genome organization and transcription mechanisms. Chromatin structure and epigenetic regulation. Post-transcriptional regulations: alternative splicing, nuclear transport, editing, microRNAs.