USP Bioproduction processes

Master the concepts of culture processes in correlation with cell growth models, in order to drive and control a bioprocess via a bioreactor. Apply the concepts of kinetics and yield to establish production balances.

Bioproduction, Process Engineering, Instrumentation, Mathematics courses in S5, S6, S7 or equivalent.

Mathematical models of cell growth for applications in cultivation processes.The different cell cultivation processes: batch, fed-batch, continuous with or without biomass recycling: strategy, simulation, set-up, operation and control via a bioreactor.Assessment of biological reactions during cultivation processes: kinetics, productivities, yields, material balance.Notions of scaling-up and -down.