Mammalian cell biology I: Cell biology

Know and understand the main elements of regulation, both positive and negative, of the cell cycle.
Know the organization and dynamic structuring of the cytoskeleton. Mobilize knowledge of energy metabolism to understand energy and carbon management at the cellular level in different physiological and environmental contexts.
Analyze, contextualize and orally present information contained in a scientific article (communication). Interpret quantitative data contained in a report or article (modeling).

Cell Biology I:

Description of the cell cycle, the main oncogenes and tumor suppressors, and the main cell signaling pathways.
Presentation of the structural dynamics of the cytoskeleton, its role in shape maintenance and cell division.
Description of the main glycosylation motifs and role of glycosylation
Regulation of glycolysis: Description of the limiting enzymatic steps - local control of glycolysis (role of PFK2) - global control of glycolysis (role of Glucagon).
Sensitivity analysis, applications to prokaryotic and eukaryotic cell metabolism.
Basics of cell culture (cell line establishment, metabolism and culture media, adherent and suspension cultures), methods for quantifying cell cycle stages, methods for quantifying mitochondrial respiration.